He began acting within films like 1996's Sleepers and 1997's Inventing the Abbotts. Since so, he has been around several films however regularly comes back to stage acting.

He's been a voice of MasterCard "Priceless" commercials since 1997, making his first appearance around an ad inside 2005.

He dated actress Mary Louise Parker since 1996 and received negative publicity whilst it broke higher inside 2003 when she was seven months pregnant, and he was seen by owning actress Claire Danes. Danes & Crudup each confirmed it were dating in 2004.

Billy Crudup starred in the production of The Pillowman, also starring Jeff Goldblum, in Broadway within Future York, which closed on September 18 2005.

Filmography
The Good Shepherd (2006) Trust the Man (2005) Stage Beauty (2004) - Ned Kynaston Big Fish (2003) - Will Bloom Charlotte Gray (2001) - Julien Levade World Traveler (2001) - Cal Almost Famous (2000) - Russell Hammond Waking the Dead (2000) - Fielding Pierce ''Jesus' Son (1999) - FH The Hi-Lo Country (1998) - Pete Calder Without Limits (1998) - Steve Prefontaine Snitch (1998) - Teddy Princess Mononoke (1997) - (voice: English version) Ashitaka Grind (1997) - Eddie Dolan Inventing the Abbotts'' (1997) - John Charles 'Jacey' Holt Everyone Says I Love You (1996) - Ken Sleepers (1996) - Tommy Marcano